Pharmaceutical Chemistry


The discipline Pharmaceutical chemistry plays a vital role in design and synthesis of new molecules using synthetic organic chemistry, the creation of biological knowledge and medicinal applications makes a major contribution to the identification and development of small drug-like molecules in the discovery process. The target structural information will be obtained from ligand-protein structures, enzyme data derived from computational, modeling and biological experiments. The potential for speedy optimization of drug discovery by selective and carefully design combinatorial small libraries along with rapid, sensitive and specific assay procedures are being explored. Natural products with desired biological activity at nanomolar range are being considered as lead compounds for further development. Computer Aided Drug Design speeds up the drug development process, 3D models are generated, novel drug candidates designed and virtual screening done in search of active compounds by using online software also. The department is actively involved in design and execution of projects related to synthetic chemistry or natural products. In-vitro screening of compounds (synthetic and natural) for various biological activities like ant-inflammatory, anti-bacterial, anti-convulsant etc are also part of research work. Synthesis of active pharmaceuticals qualitative and quantitative analysis of marketed drugs are part of our regular activities.


1. Dr. B. Nagasudha
Professor & HOD
2. Mr. T. Rajkumar
3. Mr .N.Yellasubbaiah
4. Ms.M.Sai Harika
5. Mrs.M.Laxmi Mrudula
6.Ms.A.M.Venu Madhavi



Equipments available in our laboratories

1. Digital balances
2. Electric heating mantles
3. Electric oil baths
4. Vacuum pumps
5. Hot air ovens
6. TLC visualization chamber
7. De-ionizer
8. Fumes cup-boards
9. Magnetic stirrer with hot plates
10. Mechanical stirrers
11. Electrical water baths
12. Colorimeter
13. pH meters
14. Centrifuges
15.Digital melting point apparatus
16. Column chromatography
17. Hot plates
18. Domestic microwave oven
19. Pipette pumps
20. Arsenic apparatus
21. Distillation units
22. Microscopes
23. Refrigerators
24. Desiccators
25. Micropipettes

Projects carried out

1.Solvent Free Synthesis of some Schiff, s Bases, their characterization and pharmacological evaluation.

2. Synthesis and characterization of several valinamide derivatives.

3.Solvent Free Synthesis of chalcones their characterization and pharmacological evaluation.

4.Synthesis, characterization and anthelmintic activity of 3-(4-acetyl-5-phenyl-4,5-dihydro-1,3,4-oxadiazol-2-yl)- 2h-chromen-2-one derivatives.

5. Synthesis, characterization and anti-inflammatory activity of 2,5-disubstituted 1,3,4- oxadiazole derivatives.

6.Phytochemical studies and evaluation oantioxidant activity of baliospermum montanum(Wild).

7. Analysis of Ropinirole and estimation of genotoxic impurities by gas chromatography.

8. Method development and method validation of stability indicating RP-HPLC method for pemetrexed disodium.

9. Method development and validation for API [ciprofloxacin Hl] using advanced analytical technique RRLC.

10.Synthesis, characterization and antioxidant activity of 1,3,5-trisubstituent pyrazolines.

11. Development and validation of new RP-HPLC method for simultaneous estimation of Levoceririzine HCl and montelukast sodium in bulk and pharmaceutical dosage form.

12. Synthesis, Characterization and Anticonvulsant activity of different Azole derivatives.

13. Synthesis, Characterization and Anti diabetic activity of N-thiadiazolylthiazolidinone Derivatives.

14. Synthesis, Characterization and Evaluation of Antibacterial, Antifungalactivity of 2,5- Disubstituted 1,3,4-Oxadiazole derivatives.

15. Synthesis , characterization and antioxidant and anti inflammatory activities of some novel chalcones and 1,3,5-trisubstituted pyrazolines.

16. Synthesis and characterization of anti oxidant and anti inflammatory activity evaluation of chalcones and pyrazoline derivatives.

17.Synthesis characterization and biological activity evaluation of some novel substituted 1,3,4- oxadiazole derivatives.

18.Synthesis of novel pyrrole derivatives as anti-mycrobacterial agents using TOSMIC reagent.

19.Synthesis, Characterization and Antioxidant and antimicrobial evaluation of coumarinylthiazoleazo-dyes.

20.Synthesis, Characterization and Antioxidant and antimicrobial evaluation of substituted Coumarinyltriazolethiadiazoles.

21.Synthesis, Characterization and Antioxidant and anti-inflamatory activity of some substituted pyrazole derivatives.

22.Evaluation of cardioprotective and invitroantioxidant activity of whole plant of SolanumSurattenceBurm. f. on isopretinol induced myocardialinfraction in rats.

23. Evaluation of antiulcer and in-vitro antioxidant activities of Rosa damascena mill.

24. Synthesis of 1,3,4-oxadiazoles from fatty acids and their anti-microbial studies.

25.Synthesis, characterization and anticonvulsant activity of substituted imidazolinone derivatives.

26. Synthesis, Characterization And Evaluation Of Some Cyanopyridine Derivatives

27. Synthesis, characterization and antimicrobial & antioxidant activity of 2-Isonicotinoyl-5- methyl-2,4-dihydro-3H-pyrazolone derivatives.

28. Synthesis, characterization and in-vitro anti inflammatory activity of oxadiazole derivatives.

29.Synthesis, characterization and biological evaluation of some amino-pyrimidine deratives.

30. Synthesis, characterization and biological evaluation of 2-Naphthyl hydrazone derivatives.

31. Synthesis, characterization and biological evaluation of some novel 2-amino pyrimidine derivatives.


1. B Naga Sudha, C Sridhar, YSR Reddy, K Swathi, S Joythi, E Venkata Siva Prasad, P Naresh, Raja Chakraborty,Saikat Sen. Synthesis and characterization of several valinamide derivatives.Journal of Chemical andPharmaceutical Research (ISSN: 0975- 7384) 2010; 2(4): 410-414.

2. B Naga Sudha, C Sridhar, VG Sastry, YSR Reddy, O Sreevidya, S Lavanya, V AshaJyothi, V Nagesh, SaikatSen, Raja Chakraborty. Synthesis, characterisation and anthelmintic activity of 3-(4-acetyl-5-phenyl-4,5-dihydro- 1,3,4-oxadiazol-2-yl)- 2h-chromen-2-one derivatives. Indian Journal of Chemistry (ISSN: 0975-0983,Impact Factor: 0.648) 2013; 52B (March):422- 427.

3. B. NagasudhaN.Yellasubbaiah, Synthesis, characterization and anticonvulsant activity of sustitutedimidazolinone derivatives, Indian Journal of Heterocyclic Chemistry, (Oct-Dec 2014)

4. B. Naga sudha, G. Venkateswarlu, Y. Sivaramireddy, S. V. Suresh kumar, H. G. Raghavendra, H. M. Sudheerkumar, Evaluation of antiulcer and in-vitro antioxidant activities of Rosadamascena mill. Asian Journal of Phytomedicine and Clinical Research 2(2), 2014, 79-92.

5. Sudha BN,Harika MS, Synthesis & characterization of N-thiadiazolylthiazolidinone derivatives, Int J Res Pharm Sci 2014, 4(2) ; 13 – 16.

6. B.NagaSudha , M. SaiHarika, H.G Raghavendra, Synergistic Activity of Thiadiazole And Thiazolidinone Derivatives Against Alloxan Induced Diabetes In Rats, Sch. Acad. J. Pharm., 2014; 3(3): 301-305.

7.Synthesis, Characterization And Evaluation Of Some Cyanopyridine Derivatives Published in World Journal of Pharmacy and Pharmaceutical Sciences.( Rajkumar et al,Synthesis, Characterization And Evaluation Of Some Cyanopyridine Derivatives,WJPPS, Vol 3, Issue 7, 2014.p 956.

8. AnuradhaKhuntia, Sujit Kumar Mohanty, Pharmacognostical& Preliminary Phytochemical Investigation of Cleome Rutidosperma Aerial Parts, International Journal of Research in Pharmacy and Science. (2013) 3 (3) 67-77.

9. Sujit Kumar Mohanty Synthesis, characterization and antimicrobial & antioxidant activity of 2-Isonicotinoyl-5-methyl-2,4-dihydro-3H-pyrazolone derivatives. Indo American Journal of Pharm Research. 2014: 4(5).

10. Anudha.khuntia, Sujit kumar, M. Sai Harika, "Hepatoprotective Activity of Ethanol Extract of Cleomereutidosperma Aerial Parts against Carbon Tetrachloride Induced Hepatotoxicity in Albino Rats", Sch.Acad.J.Pharm., 2014; 3(3): 246-49.

Seminars conducted
A two day National level work shop on Green Chemistry-role in environment protection.

Seminars attended

1. Two day National level workshop on analytical techniques in research and analysis at JNTUA
college of Engineering, Pulivendula
2. Faculty training programme on “ Teaching methodologies” conducted by national institute of
technical teachers training and research at BITS Kurnool.
3. Molecular modeling at BITS Hyderabad.
4.Biodiversity –Our insurance for the future at Govt. degree college for men, Kurnool.





 Time Table : B.Pharmacy II-I, III-I & IV-I Regular & Supplimentary Nov / Dec '2018 Examinations

Academic Calendar B.Pharmacy I yr I Sem (for 2018 admitted batch)

Academic Regulations(R15) for B.Pharmacy

Academic Calendar June'2018 -  BPharmacy II-I, III-I & IV-I

 Regular Classwork for B.Pharmacy I yr I sem & Pharm D I yr will commences from 24-09-2018.

Pharm D

Academic Calendar Pharm D I yr (for 2018 admitted batch)

Academic Regulations (2014-15)  

Pharm.D and Pharm.D (P.B) - R17 Course Structure & Syllabi

Pharm.D & Pharm.D (P.B) Modifications 03-10-2018


 M.Pharmacy (2018-19) Academic Calendar



We are Happy to inform to you that our application was successfully processed and our journal was allotted with the ISSN NO

OUR ISSN NO IS : 2395-4779



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Chinnatekur | Kurnool 518218